Enzalutamide
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Enzalutamide  (Synonyms: MDV3100)

Cas No. : 915087-33-1
Category : Anti Cancer
Sub-Category : Others

Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells.

Description :

An androgen-receptor (AR) antagonist with IC50 of 36 nM; reduces the efficiency of AR nuclear translocation, and impairs both DNA binding to androgen response elements and recruitment of coactivators; induces tumor regression in mouse models of castration-resistant human prostate cancer; orally available.

Prostate cancer

Approved

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